Flavios Herakleios Konstantinos was known even in Byzantine sources as Constans to avoid confusion with his father Herakleios Konstantinos (known as Constantine III), his uncle and second cousin Konstantinos Herakleios (known as Herakleonas) and his son, Constantine IV. He became emperor following the deposition of his uncle and second cousin Herakleonas in 641, itself following the death of Constans' father, Constantine III, and grandfather, Herakleios, all in 641. Constans spent much time in Sicily and was reputed to have desired to move the capital to Syracuse, where he set up a mint. He was murdered in Syracuse in favour of the usurper Mezezios, who was in turn removed by Constans' eldest son, Constantine IV.

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